Sex and Gender Differences in Testing, Hospital Admission, Clinical Presentation, and Drivers of Severe Outcomes From COVID-19.

Eileen P ScullyGrant SchumockMartina FuGuido MassaccesiJohn MuschelliJoshua F BetzEili Y KleinNatalie E WestMatthew RobinsonBrian T GaribaldiKaren Bandeen-RocheScott ZegerSabra L KleinAmita Gupta

Published in: Open forum infectious diseases (2021)

Higher inflammatory laboratory test values were associated with increased risk of severe coronavirus disease 2019 for males. A sex-specific inflammatory response to SARS-CoV-2 infection may underlie the sex differences in outcomes.

Keyphrases

coronavirus disease
inflammatory response
respiratory syndrome coronavirus
early onset
sars cov
emergency department
healthcare
lipopolysaccharide induced
oxidative stress
lps induced
drug induced
metabolic syndrome
toll like receptor
insulin resistance
skeletal muscle
glycemic control