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Neuropsychological Impairments and Their Cognitive Architecture in Mild Cognitive Impairment (MCI) with Lewy Bodies and MCI-Alzheimer's Disease.

Joanna CiafoneAlan ThomasRory DurcanPaul C DonaghyCalum A HamiltonSarah LawleyGemma RobertsSean CollobyMichael J FirbankLouise AllanGeorge PetridesJohn-Paul TaylorJohn T O'BrienPeter Gallagher
Published in: Journal of the International Neuropsychological Society : JINS (2021)
MCI-LB was characterized by executive dysfunction and slowed processing speed but did not show the visuospatial dysfunction expected, while MCI-AD displayed an amnestic profile. However, there was considerable neuropsychological profile overlap and processing speed mediated performance in both MCI subtypes.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • working memory
  • oxidative stress