Effect of Sleep Disturbance Symptoms on Treatment Outcome in Blended Cognitive Behavioral Therapy for Depression (E-COMPARED Study): Secondary Analysis.
Esben Skov JensenNicolai LadegaardAngelina Isabella MellentinDavid Daniel EbertIngrid TitzlerRicardo Araya BaltraArlinda Cerga PashojaJean-Baptiste HazoJérôme HoltzmannRoman CieslakEwelina SmoktunowiczRosa María BañosRocio HerreroAzucena García-PalaciosCristina BotellaThomas BergerTobias KriegerTrine Theresa HolmbergNaira TopoocoGerhard AnderssonAnnemieke van StratenLise L KemmerenAnnet KleiboerHeleen RiperKim MathiasenPublished in: Journal of medical Internet research (2022)
Baseline sleep disturbance symptoms may have a negative impact on long-term treatment outcomes in bCBT for MDD. This effect was not observed for TAU. These findings suggest that special attention to sleep disturbance symptoms might be warranted when MDD is treated with bCBT. Future studies should investigate the effect of implementing modules specifically targeting sleep disturbance symptoms in bCBT for MDD to improve long-term prognosis.