Combination release of chemokines from coated coils to target aneurysm healing.
Dimitri LaurentBrandon P Lucke-WoldWilliam S DoddMelanie MartinezMuhammad Abdul Baker ChowdhuryKoji HosakaKartik MotwaniBrian HohPublished in: Journal of neurointerventional surgery (2022)
This study demonstrates that MCP-1 and OPN coated coils are viable and may promote early aneurysm healing. Dual coated coils may have synergistic benefit given different location of protein interaction measured in vivo. Further work is warranted.