Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer.
Valentina HoyosSpyridoula VasileiouManik KuvalekarAyumi WatanabeIfigeneia TzannouYovana VelazquezMatthew French-KimWingchi K LeungSuhasini LullaCatherine RobertsonClaudette ForemanTao WangShaun BulsaraNatalia LaptevaBambi GrilleyMatthew EllisCharles Kent OsborneAngela CoscioJulie NangiaHelen E HeslopCliona M RooneyJuan F VeraPremal LullaMothaffar RimawiAnn M LeenPublished in: Therapeutic advances in medical oncology (2022)
T-cell expansion, persistence, and antigen spreading. Future directions of this approach may include additional strategies to enhance the therapeutic benefit of multiTAA T cells in patients with BC.