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ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential.

Anne E HallMelinda A EngevikNuman OezguenAnthony HaagJames Versalovic
Published in: Microbial cell factories (2019)
Histamine production is a potentially beneficial feature for intestinal microbes by promoting long-term colonization and suppression of inflammation and host immune responses. ClC transporters may serve as tunable modulators for histamine production by L. reuteri and other gut microbes.
Keyphrases
  • immune response
  • oxidative stress
  • small molecule
  • machine learning
  • deep learning
  • dendritic cells
  • toll like receptor
  • reactive oxygen species
  • human health
  • climate change
  • quantum dots
  • energy transfer