Login / Signup

MiR-499a-5p Inhibits Proliferation, Invasion, Migration, and Epithelial-Mesenchymal Transition, and Enhances Radiosensitivity of Cervical Cancer Cells via Targeting eIF4E.

Xiaobin GuMeilian DongZheyan LiuJing YangYonggang Shi
Published in: OncoTargets and therapy (2020)
MiR-499a-5p promoted the apoptosis and radiosensitivity and inhibited proliferation, invasion, migration, and EMT by directly targeting eIF4E in CC cells.
Keyphrases
  • epithelial mesenchymal transition
  • cell cycle arrest
  • signaling pathway
  • induced apoptosis
  • cell migration
  • endoplasmic reticulum stress
  • cell death
  • pi k akt
  • cancer therapy
  • transforming growth factor
  • oxidative stress