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Anti-cancer effect of entacaponeon esophageal cancer cells via apoptosis induction and cell cycle modulation.

Fahimeh RamedaniSeyyed Mehdi JafariMarie Saghaeian JaziZeinab MohammadiJahanbakhsh Asadi
Published in: Cancer reports (Hoboken, N.J.) (2022)
Our findings suggested that entacapone has the inhibitory effect on ESCC cell lines through induction of the apoptosis and modulation of the cell cycle without toxicity on the normal PBMC.
Keyphrases
  • cell cycle
  • oxidative stress
  • cell proliferation
  • endoplasmic reticulum stress
  • cell cycle arrest
  • cell death
  • pi k akt
  • signaling pathway