Anti-cancer effect of entacaponeon esophageal cancer cells via apoptosis induction and cell cycle modulation.

Fahimeh RamedaniSeyyed Mehdi Jafari Marie Saghaeian JaziZeinab MohammadiJahanbakhsh Asadi

Published in: Cancer reports (Hoboken, N.J.) (2022)

Our findings suggested that entacapone has the inhibitory effect on ESCC cell lines through induction of the apoptosis and modulation of the cell cycle without toxicity on the normal PBMC.

Keyphrases

cell cycle
oxidative stress
cell proliferation
endoplasmic reticulum stress
cell cycle arrest
cell death
pi k akt
signaling pathway