Analysis of Vibrio cholerae genomes identifies new type VI secretion system gene clusters.

Cristian V CrisanAroon T ChandeKenneth WilliamsVishnu RaghuramLavanya RishishwarGabi SteinbachSamit S WatvePeter YunkerI King JordanBrian K Hammer

Published in: Genome biology (2019)

We develop a novel bioinformatics method and identify new T6SS gene clusters in V. cholerae. We also show the TleV1 toxin is delivered in a T6SS manner by V. cholerae and can lyse other bacterial cells. Our web-based tool can be modified to identify additional novel T6SS genomic loci in diverse bacterial species.

Keyphrases

genome wide
copy number
dna methylation
induced apoptosis
escherichia coli
genome wide identification
cell cycle arrest
endoplasmic reticulum stress
gene expression
genome wide analysis
transcription factor
genome wide association study
genome wide association