Brain proton magnetic resonance spectroscopy and neurodevelopment after preterm birth: a systematic review.

Burcu CebeciThomas AlderliestenJannie P WijnenNiek E van der AaManon J N L BendersLinda S de VriesAgnes van den HoogenFloris Groenendaal

Published in: Pediatric research (2021)

In preterm born infants, brain metabolism assessed using 1H-MRS at term-equivalent age is associated with motor, cognitive, and language outcomes at 18-24 months. 1H-MRS at term-equivalent age in preterm born infants may be used as an early indication of brain development. Specific findings relating to NAA were most predictive of outcome.

Keyphrases

gestational age
preterm birth
low birth weight
preterm infants
resting state
white matter
functional connectivity
cerebral ischemia
autism spectrum disorder