A prediction model for early systemic recurrence in breast cancer using a molecular diagnostic analysis of sentinel lymph nodes: A large-scale, multicenter cohort study.

Tomo OsakoMasaaki MatsuuraDaisuke YotsumotoShin TakayamaKoji KanekoMina TakahashiKenzo ShimazuKatsuhide YoshidomeKazuya KuraokaMasayuki ItakuraMayumi TaniTakashi IshikawaYasuyo OhiTakayuki KinoshitaNobuaki SatoMasahiko TsujimotoSeigo NakamuraHitoshi TsudaShinzaburo NoguchiFutoshi Akiyama

Published in: Cancer (2022)

Using the OSNA assay, the molecular readout-based SN tumor burden is an independent prognostic factor for early breast cancer. This model accurately predicts early systemic recurrence and may facilitate decision-making related to treatment.

Keyphrases

prognostic factors
early breast cancer
lymph node
decision making
high throughput
single molecule
drug induced
early stage
combination therapy
neoadjuvant chemotherapy
double blind
sentinel lymph node
single cell
childhood cancer