Activated platelets kill Staphylococcus aureus, but not Streptococcus pneumoniae-The role of FcγRIIa and platelet factor 4/heparinantibodies.
Martina WolffStefan HandtkeRaghavendra PalankarJan WescheThomas P KohlerChristian KohlerYves GruelSven HammerschmidtAndreas GreinacherPublished in: Journal of thrombosis and haemostasis : JTH (2020)
Anti-PF4/H antibodies seem to have only a minor role for direct killing of Gram-positive bacteria by platelets. Staphylococcus aureus is killed by platelets or platelet releasate. In contrast, S. pneumoniae affects platelet viability.