Genetic Counseling and Germline Testing in the Era of Tumor Sequencing: A Cohort Study.
Stefan KlekBrandie H LeachAlex MilinovichYing NiJame AbrahamHaider MahdiBassam EstfanAlok A KhoranaBrian J BolwellPetros GrivasDavendra P S SohalPauline FunchainPublished in: JNCI cancer spectrum (2020)
Both review of tumor-only NGS by genetics and the institution of a process coordinating GC with oncology appointments increased the discovery of germline pathogenic variants from tumor-only NGS testing. Furthermore, this process identified germline pathogenic variant carriers who would not have otherwise met standard criteria for germline testing.