Rate of reoperation at 1 year for aortic repair vs replacement in aortic regurgitation. A trial sequence analysis of published meta-analysis results.
Ashish K UmeshMariam ShariffPublished in: Journal of cardiac surgery (2019)
The pooled estimate of a recent meta-analysis concluded that rate of reoperation at 1 year was significantly higher in Aortic valve repair (8.82% vs 3.70%) as compared with aortic valve replacement in patients with aortic regurgitation (odds ratio = 2.67, 95% confidence interval [1.08, 3.62], P = .03). We performed a trial sequential analysis using the published data of the meta-analysis and found the evidence is not strong enough for the conclusion.
Keyphrases
- aortic valve
- aortic valve replacement
- systematic review
- aortic stenosis
- transcatheter aortic valve implantation
- meta analyses
- transcatheter aortic valve replacement
- phase iii
- study protocol
- clinical trial
- left ventricular
- phase ii
- case control
- heart failure
- electronic health record
- open label
- deep learning
- atrial fibrillation
- coronary artery
- artificial intelligence