Association between OX40L polymorphism and type 2 diabetes mellitus in Iranians.

Abdolreza Sotoodeh Jahromi Saiedeh Erfanian Abazar Roustazadeh

Published in: BMC medical genomics (2024)

Our findings revealed that OX40L promoter gene polymorphisms are associated with T2DM. Moreover, genotype and allelic variations were related to the decreased risk of T2DM in Iranians. Further studies are recommended to show whether these polymorphic variations could affect OX40/OX40L interaction or OX40L phenotype.

Keyphrases

low density lipoprotein
gene expression
transcription factor
type diabetes
insulin resistance