Down-regulation of CORO1C mediated by lncMALAT1/miR-133a-3p axis contributes to trophoblast dysfunction and preeclampsia.
Hanhui NieXiufang WangXiaohui DongYiling WeiJiachun WeiKa Cheuk YipQiao ZhangRuiman Li
Published in: Placenta (2024)
This study demonstrated that the dysregulation of CORO1C via lncMALAT1/miR-133a-3p axis impairs trophoblast function and contributes to preeclampsia pathogenesis, providing novel insights in PE therapy through modulating CORO1C level.