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Novel hepatitis B virus infection mouse model using herpes simplex virus type 1 thymidine kinase transgenic mice.

Ayumu KanbeTetsuya IshikawaAkira HaraHiroshi SuemizuEri NanizawaYuki TamakiHiroyasu Ito
Published in: Journal of gastroenterology and hepatology (2020)
A novel HBV infection mouse model will help to understand the mechanisms of HBV tolerance similar to human chronic HBV-infected patients and can be used to develop a new strategy to treat chronic HBV infection.
Keyphrases
  • hepatitis b virus
  • mouse model
  • liver failure
  • herpes simplex virus
  • tyrosine kinase
  • drug induced
  • induced pluripotent stem cells