Repeated Administration of the Cannabinoid WIN Alters the Isoflurane-Sparing Effect of Morphine and Dexmedetomidine.

José Antonio IbancovichiJulio Raúl Chávez-MonteagudoPedro Sánchez-AparicioMarco Antonio De Paz-Campos

Published in: Veterinary sciences (2023)

Medication with a cannabinoid for 21 days augmented the MAC of isoflurane. The sparing effect of morphine on isoflurane is lower in rats constantly medicated with a cannabinoid. The sparing effect of dexmedetomidine on the minimum alveolar concentration of isoflurane is greater in rats repeatedly medicated with a cannabinoid.

Keyphrases

robot assisted
cardiac surgery
acute kidney injury
minimally invasive
adverse drug
emergency department
virtual reality