IL-6, IL-1β and TNF-α regulation of the chondrocyte phenotype: a possible mechanism of haemophilic cartilage destruction.
Liujie ZhengZhiwei HanDasheng LuoJiale LiNanyu PangMingyang DingHoulong YeKeyan ZhuYunfeng YaoPublished in: Hematology (Amsterdam, Netherlands) (2023)
These findings suggest that IL-6, IL-1β and TNF-α may be involved in haemophilic cartilage destruction pathogenesis by altering the chondrocyte phenotype through modulation of FGF23 and SOX9 gene expression.