MOTS-c Peptide Attenuated Diabetic Cardiomyopathy in STZ-Induced Type 1 Diabetic Mouse Model.

Nan WuCaijie ShenJian WangXiaomin ChenPeng Zhong

Published in: Cardiovascular drugs and therapy (2023)

Our data demonstrated a protective effect of MOTS-c against diabetic cardiomyopathy potentially by activating the AMPK pathway and inhibiting inflammation. These findings demonstrate the therapeutic efficacy of MOTS-c for diabetic cardiomyopathy and warrant further investigation into its clinical potential.

Keyphrases

type diabetes
wound healing
heart failure
mouse model
diabetic rats
signaling pathway
oxidative stress
machine learning
atrial fibrillation
risk assessment
drug induced
climate change
human health
artificial intelligence