Wharton's jelly mesenchymal stem cells embedded in PF-127 hydrogel plus sodium ascorbyl phosphate combination promote diabetic wound healing in type 2 diabetic rat.

Yiren JiaoXiaolin ChenYongxia NiuSunxing HuangJingwen WangMingxun LuoGuang ShiJunjiu Huang

Published in: Stem cell research & therapy (2021)

PF-127 plus SAP combination facilitates WJMSCs-mediated diabetic wound healing in rat through promoting cell survival, the macrophage transformation, and angiogenesis. Our findings may potentially provide a helpful therapeutic strategy for patients with diabetic cutaneous ulcer.

Keyphrases

wound healing
mesenchymal stem cells
umbilical cord
oxidative stress
adipose tissue
type diabetes
bone marrow
stem cells
endothelial cells