A three-dimensional DNA walker amplified FRET sensor for detection of telomerase activity based on the MnO2 nanosheet-upconversion nanoparticle sensing platform.

Mingdi Xu Junyang ZhuangXiaoyu JiangXinzhong LiuDianping Tang

Published in: Chemical communications (Cambridge, England) (2019)

A novel fluorescent sensing platform for telomerase activity assay was developed by coupling a three-dimensional (3D) DNA walker with the MnO2 nanosheet-upconversion nanoparticle (UCNPs) complex-based fluorescence resonance energy-transfer (FRET) system.

Keyphrases

energy transfer
quantum dots
high throughput
single molecule
circulating tumor
cell free
label free
living cells
sensitive detection
room temperature
nucleic acid
loop mediated isothermal amplification
electron transfer