Liposome encapsulation and EDTA formulation of dsRNA targeting essential genes increase oral RNAi-caused mortality in the Neotropical stink bug Euschistus heros.

Nathaly L CastellanosGuy SmaggheRohit SharmaEugênio Eduardo de Oliveira Olivier Christiaens

Published in: Pest management science (2018)

The results demonstrate that continuous ingestion of dsRNA with EDTA or liposome-encapsulated dsRNA can prevent dsRNA from being degraded enzymatically and suggest great potential for using these formulations in dsRNA delivery to use RNAi as a functional genomics tool or for pest management of stink bugs. © 2018 Society of Chemical Industry.

Keyphrases

drug delivery
cardiovascular events
cardiovascular disease
single cell
gene expression
climate change
genome wide identification