A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening.

Qing SunLarry PastorJinwei DuMichael J PowellAiguo ZhangWalter BodmerJianzhong WuShu ZhengMichael Y Sha

Published in: PloS one (2021)

The XNA-mediated molecular clamping assay is a rapid, precise, and sensitive assay for the detection of precancerous lesions cfDNA and CRC cfDNA or FFPE samples.

Keyphrases

colorectal cancer screening
loop mediated isothermal amplification
high throughput
single molecule