Bridging Reduced Grip Strength and Altered Executive Function: Specific Brain White Matter Structural Changes in Patients with Alzheimer's Disease.

Shan-Wen LiuXiao-Ting MaShuai YuXiao-Fen WengMeng LiJiangtao ZhuChun-Feng LiuHua Hu

Published in: Clinical interventions in aging (2024)

Reduced grip strength in AD patients is associated with extensive impairment of WM structural integrity. Changes in FDC of specific WM fiber tracts related to executive function play a significant mediating role in the reduction of grip strength in AD patients.

Keyphrases

end stage renal disease
white matter
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
cognitive decline
patient reported
functional connectivity