Connecting Hindered Transport in Porous Media across Length Scales: From Single-Pore to Macroscopic.

Hindered mass transport is widely observed in various porous media; however, there is no universal model capable of predicting transport in porous media due to the heterogeneity of porous structures and the complexity of the underlying microscopic mechanisms. Here, we used a highly ordered porous medium as a model system to directly explore the effects of geometric parameters (i.e., pore size, pore throat size, and tracer particle size) and microscopic interaction parameters (e.g., controlled by ionic strength) on nanoparticle transport in porous environments using single-particle tracking. We found a linear scaling relation between the macroscopic diffusion coefficient and microscopic diffusion behavior involving a combination of parameters associated with pore-scale features and phenomena, including both geometric effects and particle-wall interactions. The proportionality coefficient relating micro and macro behaviors was complex and related to the connectivity of the matrix and the pore-size variation, which could lead to tortuous diffusion pathways, hindering macroscopic transport.