Periodontitis-induced oral microbiome alterations provide clues on how periodontitis exacerbates colitis.

Xiaoxue WangYilin LuoYanlan HuangZhiheng JinZhichao LiJunyu ChenFei HuXueyang ZhangXiaohui Rausch-Fan

Published in: Journal of clinical periodontology (2022)

Our study revealed that alteration in periodontitis-induced microbial metabolites deteriorated colitis in a mouse model and that this was associated with Ile production.

Keyphrases

mouse model
high glucose
diabetic rats
drug induced
microbial community
oxidative stress
ulcerative colitis