Orthotopic liver transplant in the pregnant recipient: A systematic review of preoperative management and maternal and fetal outcomes.
Diana N RomanoDebbie C MokuoluDaniel J KatzSamuel DeMariaPublished in: Clinical transplantation (2021)
Severe liver dysfunction requiring transplantation is a major event at any stage of life, but for those requiring liver transplantation while pregnant, two lives hang in the balance. Available evidence on this relatively rare event consists solely of case reports and have yet to be reviewed or synthesized. We performed a systematic literature review and analyzed reports of 22 patients who underwent liver transplantation during pregnancy. This review describes the reported etiologies of hepatic failure in pregnant patients requiring transplantation, perioperative anesthetic management techniques, and the maternal and fetal clinical outcomes.
Keyphrases
- end stage renal disease
- ejection fraction
- pregnant women
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- stem cells
- emergency department
- patient reported outcomes
- oxidative stress
- metabolic syndrome
- acute kidney injury
- cardiac surgery
- body mass index
- birth weight
- mesenchymal stem cells
- preterm birth
- pregnancy outcomes
- weight gain