Novel metabolic biomarker for early detection and diagnosis to the patients with gastric cardia adenocarcinoma.

Meng Xia WeiZheng YangPan Pan WangXue Ke ZhaoXin SongRui Hua XuJing Feng HuKan ZhongLing Ling LeiWen Li HanMiao Miao YangFu You ZhouXue Na HanZong Min FanJia LiRan WangBei LiLi Dong Wang

Published in: Cancer medicine (2024)

A total of 25 common and stable differential metabolites may hold promise as liquid non-invasive indicators for GCA diagnosis. HER2 may function as a tumor suppressor gene in GCA, as its overexpression is associated with improved survival. The downregulation of bile acid metabolism in GCA may offer valuable theoretical insights and innovative approaches for precision-targeted treatments in GCA patients.

Keyphrases

end stage renal disease
cell proliferation
ejection fraction
chronic kidney disease
newly diagnosed
squamous cell carcinoma
ms ms
prognostic factors
peritoneal dialysis
big data
gene expression
patient reported outcomes
drug delivery
free survival
ionic liquid
patient reported
genome wide identification