Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model.

Chloë GoossensRuben WeckxSarah DerdeLawrence Van HelleputteDominik SchneidereitMichael HaugBarbara ReischlOliver FriedrichLudo Van Den BoschGreet Van den BergheLies Langouche

Published in: Journal of cachexia, sarcopenia and muscle (2021)

Prolonged sepsis-induced muscle weakness may predominantly be related to a disruption in myofibrillar cytoarchitectural structure, rather than to neural abnormalities.

Keyphrases

mouse model
septic shock
acute kidney injury
skeletal muscle
intensive care unit
high glucose
diabetic rats
drug induced
resistance training
oxidative stress
african american
endothelial cells
body composition