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Long-term retention of adalimumab treatment and associated prognostic factors for 1189 patients with Crohn's disease.

Hiroki TanakaNoriko KamataAkihiro YamadaKatsuya EndoToshimitsu FujiiTakuya YoshinoTakeshi SugayaYoko YokoyamaShigeki BambaJunji UmenoYuka YanaiManabu IshiiTakaaki KawaguchiShinichiro ShinzakiYosuke ToyaTaku KobayashiMasanori NojimaToshifumi Hibinull null
Published in: Journal of gastroenterology and hepatology (2018)
Our data demonstrated a good retention rate of adalimumab in patients with Crohn's disease over a 4-year period. Female sex, perianal disease, concomitant treatment with prednisolone at baseline, previous infliximab use, higher C-reactive protein levels, and lower albumin levels were associated with poor retention of adalimumab treatment.
Keyphrases
  • prognostic factors
  • rheumatoid arthritis
  • ulcerative colitis
  • juvenile idiopathic arthritis
  • machine learning
  • systemic lupus erythematosus
  • hidradenitis suppurativa