Oncolytic Reovirus (pelareorep) Induces Autophagy in KRAS-mutated Colorectal Cancer.
Jeeshan JiffryThongthai ThavornwatanayongDevika RaoElisha J FogelDurvanand SaytooRishika NahataHillary GuzikImran ChaudharyTitto AugustineSanjay GoelRadhashree MaitraPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Pelareorep hijacks host autophagic machinery in KRAS-mut conditions to augment its propagation and preferential oncolysis of the cancer cells.