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Low-grade epilepsy-associated tumors: Epilepsy outcome and antiseizure medication discontinuation after lesionectomies as first-line surgical approach in pediatric population.

Pia BernardoMaria Rosaria ScalaAlfonso RubinoPietro SpennatoGiuseppe MironeCarmela RussoPia SantangeloEugenio CovelliGiampina GrimaldiVittoria D'OnofrioGiuseppe Cinalli
Published in: Epileptic disorders : international epilepsy journal with videotape (2024)
Our findings confirm that shorter epilepsy disease duration, monotherapy before surgery, and seizure semeiology are determinant factors for a positive seizure outcome and medication discontinuation, also with less invasive surgical approaches such as lesionectomies. However, considering the intrinsic multifactorial epileptogenic nature of LEATs, a tailored surgical approach should be considered to optimize clinical and seizure outcome, especially for lesions located in the temporal lobe.
Keyphrases
  • low grade
  • temporal lobe epilepsy
  • high grade
  • healthcare
  • minimally invasive
  • coronary artery bypass
  • emergency department
  • combination therapy
  • study protocol