Low-grade epilepsy-associated tumors: Epilepsy outcome and antiseizure medication discontinuation after lesionectomies as first-line surgical approach in pediatric population.
Pia BernardoMaria Rosaria ScalaAlfonso RubinoPietro SpennatoGiuseppe MironeCarmela RussoPia SantangeloEugenio CovelliGiampina GrimaldiVittoria D'OnofrioGiuseppe CinalliPublished in: Epileptic disorders : international epilepsy journal with videotape (2024)
Our findings confirm that shorter epilepsy disease duration, monotherapy before surgery, and seizure semeiology are determinant factors for a positive seizure outcome and medication discontinuation, also with less invasive surgical approaches such as lesionectomies. However, considering the intrinsic multifactorial epileptogenic nature of LEATs, a tailored surgical approach should be considered to optimize clinical and seizure outcome, especially for lesions located in the temporal lobe.