Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.

Junsheng LouHaojie ZhangJianjun QiYu XuXingyu WangJingtao JiangXinli HuLibin NiYuepiao CaiXiangyang WangWeiyang GaoZhou-Guang WangKailiang Zhou

Published in: British journal of pharmacology (2021)

CHBP promotes skin flap survival by upregulating autophagy and inhibiting oxidative stress in the ischemic flap and may have potential clinical applications.

Keyphrases

soft tissue
oxidative stress
cell death
signaling pathway
breast reconstruction
endoplasmic reticulum stress
dna damage
ischemia reperfusion injury
induced apoptosis
wound healing
free survival
dna binding
human health
subarachnoid hemorrhage
heat shock
neural network