Retinal layer thinning is reflecting disability progression independent of relapse activity in multiple sclerosis.
Gabriel BstehHarald HegenPatrick AltmannMichael AuerKlaus BerekFranziska Di PauliSebastian WurthAnne ZinganellPaulus Stefan RommerFlorian DeisenhammerFritz LeutmezerThomas BergerPublished in: Multiple sclerosis journal - experimental, translational and clinical (2020)
PIRA is associated with retinal thinning, likely reflecting neurodegenerative processes, not directly associated with focal inflammation. It might be a clinical measure to identify MS patients with ongoing MS-associated neurodegeneration.