Diabetes mellitus in older persons with neurocognitive disorder: overtreatment prevalence and associated structural brain MRI findings.
Pauline PutallazLaurence Seematter-BagnoudBogdan DraganskiOlivier RouaudHélène KriefChristophe J BülaPublished in: BMC geriatrics (2024)
A significant proportion of older patients with diabetes and neurocognitive disorder were subjected to excessively intensive treatment. The association identified with volume loss in several specific brain regions highlights the need to further investigate the potential cerebral damages associated with overtreatment and related hypoglycemia in larger sample.
Keyphrases
- resting state
- white matter
- cerebral ischemia
- community dwelling
- physical activity
- bipolar disorder
- middle aged
- type diabetes
- functional connectivity
- magnetic resonance imaging
- glycemic control
- risk factors
- subarachnoid hemorrhage
- combination therapy
- multiple sclerosis
- metabolic syndrome
- climate change
- skeletal muscle