Nephrotoxicity of Vancomycin in Combination with Beta-lactam Agents: Ceftolozane-tazobactam vs. Piperacillin-tazobactam.
Sara AlosaimyAbdalhamid M LagnfAthena L V HobbsMusa MubarezWesley D KufelTaylor MorrisetteRadhika S PolisettyDavid LiMichael P VeveSam P SimonJames TruongNatalie FinchVeena VenugopalanMatthew RicoLee AmayaChristine YostAshley CubillosElisabeth ChandlerMegan PatchIan Murphy Kelsey SmithMark BiagiJustin WrinW Justin MooreKyle C MolinaNicholas ReboldDana HolgerAshlan J Kunz CoyneSarah JorgensenPaige WituckiNikki N TranSusan L DavisGeorge SakoulasMichael J RybakPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Collectively, our results suggest that the AKI is not likely to be related to tazobactam but rather to the piperacillin which is a component in the VAN-TZP combination but not the VAN-C/T.