Karyotype evaluation of repeated abortions in primary and secondary recurrent pregnancy loss.
Tatiana V NikitinaElena A SazhenovaDaria I ZhigalinaEkaterina N TolmachevaN N SukhanovaIgor N LebedevPublished in: Journal of assisted reproduction and genetics (2020)
The frequency of abnormalities is higher in abortions from the secondary RPL versus primary RPL group, and this difference is due to the relative deficiency of miscarriages with abnormal karyotypes in older women with primary RPL. The probability of having the same karyotype pattern (recurrent normal or recurrent abnormal) in the previous and subsequent abortion is increased significantly compared with chance.