Benchmarking the proteomic profile of animal models of mesial temporal epilepsy.
Amanda Morato do CantoAlexandre Barcia de GodoiAlexandre H B MatosJaqueline C GeraldisFabio RogerioMarina K M AlvimClarissa L YasudaEnrico GhizoniHelder TedeschiDiogo F T VeigaBarbara HenningWelliton SouzaCristiane S RochaAndré S VieiraElayne V DiasBenilton S CarvalhoRovilson GilioliAlbert B ArulRenã A S RobinsonFernando CendesIscia Lopes-CendesPublished in: Annals of clinical and translational neurology (2022)
Our results indicate that each model has its own set of biological responses leading to epilepsy. Thus, it seems that only using a combination of the three models may one replicate more closely the mechanisms underlying MTLE+HS as seen in patients.