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1,2-Difluoroethylene (HFO-1132): synthesis and chemistry.

Liubov V SokolenkoTaras M SokolenkoYurii L Yagupolskii
Published in: Beilstein journal of organic chemistry (2024)
This article provides a comprehensive overview of the synthesis and chemistry of 1,2-difluoroethylene (HFO-1132). The major routes for the preparation of the E - and Z -isomer of HFO-1132 are reviewed, along with the chemistry in radical, nucleophilic, and electrophilic reactions.
Keyphrases
  • drug discovery
  • molecularly imprinted
  • mass spectrometry
  • high resolution
  • liquid chromatography