Association between NPPA promoter methylation and hypertension: results from Gusu cohort and replication in an independent sample.

Jing LiJinhua ZhuLiyun RenShengqi MaBin ShenJia YuRongyan ZhangMingzhi ZhangYan HeHao Peng

Published in: Clinical epigenetics (2020)

DNA methylation levels at NPPA promoter were decreased in Chinese adults with hypertension. Aberrant DNA methylation of the NPPA gene may participate in the mechanisms of hypertension.

Keyphrases

dna methylation
genome wide
blood pressure
gene expression
copy number
genome wide identification