Assessment of the Protein-Protein Interactions in a Highly Concentrated Antibody Solution by Using Raman Spectroscopy.

Chikashi OtaShintaro NoguchiSatoru NagatoishiKouhei Tsumoto

Published in: Pharmaceutical research (2015)

Our data show that Raman spectroscopy can provide valuable information of the protein-protein interactions based on conformational approaches to support conventional colloidal approaches, especially for analyses of highly concentrated solutions.

Keyphrases

raman spectroscopy
molecular dynamics
molecular dynamics simulations
single molecule
big data
health information
deep learning