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Negative SARS-CoV-2 PCR or rapid antigen test result and the subsequent risk of being infectious: a mathematical simulation study.

Ralf KrumkampBenno KreuelsVeronika K JaegerJürgen MayRafael MikolajczykAndré Karch
Published in: BMC medical research methodology (2021)
This study demonstrates that the number of infectious individuals in a screened group of asymptomatic people can be effectively reduced, and this effect can be described mathematically. However, the false negative rate of a test, the time since the negative test and the underlying SARS-CoV-2 incidence are critical parameters in determining the observed subsequent number of cases in tested population groups.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • risk factors