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Chemical entity normalization for successful translational development of Alzheimer's disease and dementia therapeutics.

Sarah MullinRobert McDougalKei-Hoi CheungHalil KilicogluAmanda BeckCaroline J Zeiss
Published in: Journal of biomedical semantics (2024)
Use of natural language models like PubMedBERT and resources such as ChEBI and PubChem provide a beneficial way to link entity mentions to ontology terms, while further supporting downstream tasks like filtering ChEBI mentions based on roles and assertions to find beneficial therapies for Alzheimer's and dementia.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • cognitive impairment
  • working memory
  • small molecule
  • autism spectrum disorder