Correlation of distribution characteristics and dynamic changes of gut microbiota with the efficacy of immunotherapy in EGFR-mutated non-small cell lung cancer.

Wei-Chi LuoShi-Qi MeiZi-Jian HuangZhi-Hong ChenYi-Chen ZhangMing-Yi YangJia-Qi LiuJing-Yan XuXiao-Rong YangRi-Wei ZhongLi-Bo TangLin-Xi YinYu DengYing-Long PengChang LuBao-Long ChenDong-Xian KeHai-Yan TuJin-Ji YangChong-Rui XuYi-Long WuQing Zhou

Published in: Journal of translational medicine (2024)

The use of antibiotics weakens immunotherapy efficacy in patients with advanced EGFR + NSCLC. The distribution characteristics and dynamic changes of gut microbiota and metabolites may indicate the efficacy of immunotherapy in advanced EGFR + NSCLC.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
advanced non small cell lung cancer
ms ms