Breast Cancer and Atrial Fibrillation.
Emanuela MauroGiovanni De LucaCecilia TettaOrlando PariseIris ParriniGianmarco PariseCarmelo Massimiliano RaoFrancesco MatteucciLinda Renata MicaliMichele Massimo GuliziaMark La MeirSandro GelsominoPublished in: Journal of clinical medicine (2022)
This study aims to establish the incidence of atrial fibrillation (AF) in breast cancer (BC) patients, focusing on staging and anti-cancer treatment. A meta-analysis was conducted to investigate the incidence of AF in BC patients and compare this incidence to other cancers. Furthermore, we evaluated the occurrence of AF as an adverse effect of biological therapies vs. non-biological therapies vs. biological therapies + non-biological therapies in BC. Finally, we compared the incidence of AF in early BC and metastatic BC. Thirty studies were included. Twenty-two studies focused on BC, encompassing 166,271 patients. In the BC group, 2.7% of patients developed AF, while in the "all cancer" group, 5.8% of patients developed AF. In addition, there was no difference between different types of therapies ( p = 0.61) and between early and metastatic BC ( p = 0.57). The type of anti-cancer therapy and the staging of BC does not influence AF's occurrence in this neoplastic disease.
Keyphrases
- atrial fibrillation
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- squamous cell carcinoma
- peritoneal dialysis
- prognostic factors
- cancer therapy
- heart failure
- risk factors
- emergency department
- patient reported outcomes
- lymph node
- drug delivery
- oral anticoagulants
- catheter ablation
- mitral valve
- direct oral anticoagulants
- electronic health record