Paediatric spinal cord low-grade gliomas-evaluation and management of post-surgical residual disease.
A H D SilvaM ConstantinidesAlexandra ValetopoulouP SgardelisKshitij MankadFelice D'ArcoI JankovicDominic N P ThompsonPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2021)
Survival rates for low-grade IMSCT are excellent. Radical micro-surgical resection, guided by IONM provides effective means of balancing the objectives of maximal safe resection, functional outcome and tumour control. Whilst evidence of 'residual disease' was identified in over 2/3 of immediate post-operative MRI scans, additional treatment was required in only 1/3 of cases. Critical appraisal of post-operative imaging findings is required to better define 'residual disease'. Small volume residual disease (<ā5%) does not compromise progression-free survival.
Keyphrases
- low grade
- free survival
- high grade
- spinal cord
- contrast enhanced
- magnetic resonance imaging
- computed tomography
- high resolution
- intensive care unit
- spinal cord injury
- emergency department
- neuropathic pain
- heart rate
- resistance training
- mass spectrometry
- diffusion weighted imaging
- combination therapy
- magnetic resonance
- body composition
- fluorescence imaging
- dual energy