Intraosseous versus intravenous vascular access during cardiopulmonary resuscitation for out-of-hospital cardiac arrest: a systematic review and meta-analysis of observational studies.

Yu-Lin HsiehMeng-Che WuJon WolfshohlJames d'EtienneChien-Hua HuangTsung-Chien LuEdward Pei-Chuan HuangEric H ChouChih-Hung WangWen-Jone Chen

Published in: Scandinavian journal of trauma, resuscitation and emergency medicine (2021)

The meta-analysis revealed no significant association between types of vascular access and neurological outcomes at hospital discharge among OHCA patients. Time to intervention was identified to be an important outcome moderator in this meta-analysis of observation studies. These results call for the need for future clinical trials to investigate the unbiased effect of IO use on OHCA CPR.

Keyphrases

cardiopulmonary resuscitation
cardiac arrest
clinical trial
systematic review
end stage renal disease
newly diagnosed
ejection fraction
case control
prognostic factors
high dose
meta analyses
skeletal muscle
current status
metabolic syndrome
open label
cerebral ischemia
phase iii