Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma.

Yuanzhuo GuFubo JiNiya LiuYongzhi ZhaoXiyang WeiShiyuan HuWei JiaXin Wei WangAnuradha BudhuJuling JiBin ZhaoStephanie RoesslerXin ZhengJunfang Ji

Published in: Journal of experimental & clinical cancer research : CR (2020)

In CSC-positive HCCs, miR-192-5p loss enhanced glycolysis and over produced lactate might further increase HCC malignant features via interacting with environmental non-tumor cells.

Keyphrases

stem cells
epithelial mesenchymal transition
human health
protein kinase
climate change