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Exploring the role of m6A modification in cancer.

Yongqi WeiYin LiChunlai Lu
Published in: Proteomics (2022)
m6A is one of the most common, abundant, and conserved post-transcriptional modifications that regulate broad biological processes in the human body through m6A regulators. m6A regulators are figuratively classified according to their functions: writers, erasers, and readers, which can methylate RNAs, demethylate RNAs, and recognize RNA m6A sites, consequently affecting RNA fate. Tumors are an essential class of diseases that threaten human health, and as the study of m6A modification in tumors continues to advance, more and more relevant studies are emerging. In this review, we overview the recent studies of m6A in various types of tumors to demonstrate the role of m6A modification in providing a vision in diagnosing and treating tumors.
Keyphrases
  • human health
  • transcription factor
  • risk assessment
  • endothelial cells
  • gene expression
  • climate change
  • case control
  • papillary thyroid
  • induced pluripotent stem cells
  • squamous cell